Common Names
Geographic Range: Native to temperate Asia; now cultivated in China, Vietnam, East Africa (Tanzania, Kenya, Madagascar), India, Brazil.
Known Contraindications
1
Compounds
3
Traditions
3
Treatments
1
Conditions
CC1CCC2C(C)C(=O)OC3OC4(C)CCC1C23OO4CYP Interaction Profile
| Enzyme | Interaction |
|---|---|
| CYP2B6 | primary substrate |
| CYP3A4 | secondary substrate |
| CYP2C19 | minor substrate |
| clinical_note | Auto-induction limits oral monotherapy. Derivatives (artesunate, artemether) used in combination therapy (ACT). CYP2B6 auto-induction is a unique pharmacokinetic feature. |
| auto_induction | Artemisinin induces its own metabolism via CYP2B6 auto-induction — decreasing plasma levels with repeated dosing |